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Psoriasis for Good -Deadly Psoriasis Consequences Revealed (study)
Most
people think of psoriasis as annoying skin disease, nothing
worse than that, and certainly not something that could be fatal.
But a new study reveals psoriasis can lay the groundwork for
something that might kill you.In July 2019, British scientists presented an eye-opening study at the British Association of Dermatologist’s 99th Annual Meeting in Liverpool. It shows that people who suffer from psoriasis are more likely than the general population is to develop certain types of cancer.
The
study is not yet available for us to analyze properly, but we expect to be able
to do that soon when it appears in the American Journal of Managed Care.
The new study was a literature review.
It looked at 50 previous studies on the relationship between psoriasis and cancer. Altogether, the surveyed studies
had 919,883 subjects in nine different countries.
People with severe psoriasis had a 22 percent higher risk of
developing all cancer types. When those with all different
severities of psoriasis were included, the increased risk
dropped to 18 percent.
People
with severe psoriasis were 7.7 times more likely than
the general population to have squamous cell carcinoma, which can occur almost
anywhere in the body. They were also 3.4 times more likely to have lymphoma,
and 3.17 times more likely to have basal cell carcinoma.
When subjects with all
severities of psoriasis were included, they found a 2.8
times higher risk for oral cavity cancer, a 2.15 times higher
risk of squamous cell carcinoma, and a twofold risk in esophageal cancer.There were also smaller increased risks for liver, laryngeal, keratinocyte, pancreatic, colorectal, and colon cancers, plus lymphoma, regardless of how severe the psoriasis was.
So
why is this happening? Well, it’s not well understood at this stage, but at
least two obvious reasons are known.
Psoriasis causes chronic and systemic inflammation, which
means that it’s everywhere in your body. Inflammation can cause small benign tumors
to get bigger and become cancerous.
Those
tiny tumors often die of starvation, but if your immune system feeds them with
inflammatory cells then they thrive.
Once
inside a tumor, they call more immune cells which causes more inflammation and,
even worse, they call molecules called cytokines. These build new blood vessels
to nourish the tumor, and so it balloons.
Secondly,
many people with psoriasis take drugs to suppress their immune systems and turn
down the inflammatory response. But if you suppress your immune system, it
can’t do all its jobs properly, and one of those jobs is fighting tumours.
That’s
why it’s so important to get the inflammation of this skin condition under
control. You need to drop alcohol, smoking, and foods that can all contribute
to the development of inflammation and cancer.
Eliminate
Psoriasis for Good - The Body Composition Type Associated with Psoriasis
If
you’re unlucky enough to have psoriasis, then you may know only too well
what triggers it for you.
Maybe it’s alcohol, smoking, stress, skin damage, sunburn, or something
else.
But
a new study in the latest edition of the Journal of Dermatology suggests that
there could be a new trigger to add to the list.
And
it’s not one you’d think of.
Researchers
have known for some time that people who are in the obese category (i.e. with a
BMI of 30+) are more likely to develop psoriasis than people with a lower body weight.
In fact, the red scaly patches that come with the condition often appear in the
skin folds that are common with obese people.
The
scientists decided to look at people who had received health screenings between
2009 and 2012 for clues, and on average, they were followed for 5.32 years.
That
meant there were more than two million subjects in the group, and 399,461 of
them were newly diagnosed with psoriasis during the follow-up period.
They
found that compared with people who had a body mass index between 18 and 23,
people with a body mass index over 30 were 11 percent more likely to develop psoriasis.
But
waist circumference turned out to be even more important than body mass index.
Those
who measured more than 41.3 inches around the belly had a 35 percent greater
risk of getting psoriasis than those with more modest
measurements between 29.5 and 31.5 inches.
The
most interesting thing they found was that the risk was highest for men with a
normal body mass index but a large waist circumference. Their risk increased by
75 percent.
This
shows (and not for the first time) why body mass index is not a good indicator
of either obesity or of health risk. It can’t measure where the fat sits on your
body, so it misses abdominal fat, which is one of the unhealthiest types, and
it doesn’t take account of extra muscle mass either.
Up
to now, researchers haven’t been entirely sure whether obesity causes psoriasis, whether psoriasis causes obesity, or whether the
relationship works in both directions.
In
this study, the abdominal obesity probably caused most of the psoriasis, as the fat was there before the
skin complaint appeared, but it’s also likely that each of them reinforces the
other, too.
In the one “direction”, fat
cells tend to turn on inflammation and compromise immune system function, which
can then cause psoriasis.And going the other way, psoriasis can contribute to obesity by putting people off taking exercise. Also, getting hot and sweaty can make clothing feel uncomfortable against the skin, so sufferers are less likely to exert themselves and may end up comfort eating too.
If
you suffer from obesity and psoriasis, then this information is probably enough
to get you down! But on the positive side, another study (in the journal JAMA
Dermatology) found that following a Mediterranean diet can help. People who did
so were much less likely to have the serious form of psoriasis.
The
Mediterranean diet also helps you to maintain a healthy weight and it contains
foods that fight inflammation.
For
more ideas to eliminate psoriasis for good, watch this video - Diet in Psoriasis - What Foods To Eat and What Foods To Avoid?
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Psoriasis for Good - The Risk Factor Behind Psoriasis
Obesity
is well known for being on the increase in the 21st century, but psoriasis not
so much. It certainly is though.
Researchers
are aware that they’re both rising, and this made them wonder whether there is
some sort of link between them.
A
new study published in the Journal PLOS Medicine by University of Bristol, the
Norwegian University of Science and Technology, and Norway’s K.G. Jebsen Center
for Genetic Epidemiology reveals that scientists have just answered this
question in a unique and creative way.
The
problem for scientists when they ask this kind of question is how to separate a
pair of conditions from all the other ones that are related to them.
Think
about it this way: obesity increases inflammation, which then increases your
risk of psoriasis. Therefore, obesity may increase the likelihood of psoriasis,
but not because obesity causes psoriasis directly.
It’s
just that obesity causes inflammation and psoriasis is sometimes the result of
that.
Or
you can look at it from a different angle. Psoriasis is unsightly,
uncomfortable and sometimes painful. This might put people off exercise, which
in turn could lead to obesity. In this case, too, the obesity and psoriasis are
not directly related, but there’s a kind of ‘stepping stone’ connection there,
with one leading to the other. The lack of exercise causes the obesity, and the
psoriasis causes the lack of exercise.
In
cases like these, the only way to be sure of whether two conditions are
causally related is by examining genes. This approach is called Mendelian
randomization.
In
other words, researchers check whether people with genes related to condition X
are more likely to have genes related to condition Y.
Focusing
on the genes cuts out the external factors, so things like physical exercise
and inflammation don’t skew the results, because they were there all along,
before any external factors entered the mix.
The
researchers got hold of genetic information for 753,421 people from the U.K.
Biobank and the Health Survey in Nord-Trøndelag.
They
did find that people who were overweight or obese had an increased risk of
psoriasis. It seems that the higher your body mass index score, the higher the
likelihood that you will have psoriasis.
To
be precise, for every single extra number on the body mass index scale, you
have a nine percent higher risk of developing psoriasis.
This
removes all doubt and clearly settles the question: there is a direct causal
link between the two conditions.
It
also tells us which one is the guilty party here: obesity is the one that
causes psoriasis, rather than the other way around.
This
doesn’t tell us anything about why this relationship exists or what mechanisms
lie behind it, but it’s still good to know.
It’s
worth mentioning that some studies show that the risk of psoriasis decreases
with weight loss, so inflammation almost certainly plays some role in enforcing
the relationship. This still doesn’t tell us why the genetic relationship is
present before the inflammation occurs though.
Given
the fact that psoriasis in Norway, for example, has increased by almost seven
percent in the last 40 years alongside the well-documented increase in obesity,
it is time that scientists improve their understanding of this relationship.
If you suffer psoriasis and want to eliminate psoriasis for good, fortunately here is an easy approach that permanently eliminates it in three weeks or less…
This
post is from the Psoriasis Program created by Julissa Clay. She provides you
with tips and techniques which she used while struggling with psoriasis.
Julissa is a natural health researcher and has written many health program
e-books and digital guides. She spent all her life to the service of all the
people and helped them to recover from various health issues naturally. You can
easily avoid the side effects of the medications by following her.
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